Entity Central Index Key
Cash equivalents and investments.
Wholesaler distribution fees and prompt pay discounts.
Reserve for returns.
Finance lease liability discounted payments due next twelve months.
Finance lease liability discounted payments due year two.
Finance lease liability discounted payments due year three.
Finance lease liability discounted payments due year four.
Finance lease liability discounted payments due year five.
Finance lease liability discounted payments due after year five.
Finance lease liability discounted excess amount.
Finance lease liability discounted debt issuance costs.
Finance lease liability discounted.
Cover [Abstract]
Document Type
Document Type
Amendment Flag
Amendment Flag
Document Period End Date
Document Period End Date
Document Fiscal Year Focus
Document Fiscal Year Focus
Document Fiscal Period Focus
Document Fiscal Period Focus
Trading Symbol
Trading Symbol
Entity Registrant Name
Entity Registrant Name
Entity Central Index Key
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Well-known Seasoned Issuer
Entity Well Known Seasoned Issuer
Entity Current Reporting Status
Entity Current Reporting Status
Entity Voluntary Filers
Entity Voluntary Filers
Entity Filer Category
Entity Filer Category
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Shell Company
Entity Shell Company
Entity File Number
Entity File Number
Entity Tax Identification Number
Entity Tax Identification Number
Entity Address, Address Line One
Entity Address Address Line1
Entity Address, Address Line Two
Entity Address Address Line2
Entity Address, City or Town
Entity Address City Or Town
Entity Address, State or Province
Entity Address State Or Province
Entity Address, Postal Zip Code
Entity Address Postal Zip Code
City Area Code
City Area Code
Local Phone Number
Local Phone Number
Entity Common Stock, Shares Outstanding
Entity Common Stock Shares Outstanding
Entity Public Float
Entity Public Float
Document Annual Report
Document Annual Report
Document Transition Report
Document Transition Report
Entity Incorporation, State or Country Code
Entity Incorporation State Country Code
Title of 12(b) Security
Security12b Title
Security Exchange Name
Security Exchange Name
Entity Interactive Data Current
Entity Interactive Data Current
ICFR Auditor Attestation Flag
Icfr Auditor Attestation Flag
Auditor Firm ID
Auditor Firm Id
Auditor Name
Auditor Name
Auditor Location
Auditor Location
Statement Of Financial Position [Abstract]
Undesignated preferred stock, par value
Preferred Stock Par Or Stated Value Per Share
Undesignated preferred stock, shares authorized
Preferred Stock Shares Authorized
Undesignated preferred stock, shares issued
Preferred Stock Shares Issued
Undesignated preferred stock, shares outstanding
Preferred Stock Shares Outstanding
Common stock, par value
Common Stock Par Or Stated Value Per Share
Common stock, shares authorized
Common Stock Shares Authorized
Common stock, shares issued
Common Stock Shares Issued
Common stock, shares outstanding
Common Stock Shares Outstanding
Purchase obligation current.
Promissory notes noncurrent.
Accrued interest noncurrent.
Credit facility noncurrent.
Purchase obligation noncurrent.
Milestone liabilities non-current.
ASSETS
Assets [Abstract]
Current assets:
Assets Current [Abstract]
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Short-term investments
Short Term Investments
Accounts receivable, net
Accounts Receivable Net Current
Inventory
Inventory Net
Prepaid expenses and other current assets
Prepaid Expense And Other Assets Current
Total current assets
Assets Current
Property and equipment, net
Property Plant And Equipment Net
Goodwill
Goodwill
Other intangible asset
Intangible Assets Net Excluding Goodwill
Long-term investments
Long Term Investments
Other assets
Other Assets Noncurrent
Total assets
Assets
LIABILITIES AND STOCKHOLDERS' DEFICIT
Liabilities And Stockholders Equity [Abstract]
Current liabilities:
Liabilities Current [Abstract]
Accounts payable
Accounts Payable Current
Accrued expenses and other current liabilities
Accrued Liabilities Current
Financing liability — current
Finance Lease Liability Current
Deferred revenue — current
Contract With Customer Liability Current
Recognized loss on purchase commitments — current
Purchase Obligation Current
Total current liabilities
Liabilities Current
Promissory notes
Promissory Notes Noncurrent
Accrued interest — promissory notes
Accrued Interest Noncurrent
Financing liability — long term
Finance Lease Liability Noncurrent
Midcap credit facility
Credit Facility Noncurrent
Senior convertible notes
Convertible Long Term Notes Payable
Recognized loss on purchase commitments — long term
Purchase Obligation Noncurrent
Operating lease liability
Operating Lease Liability Noncurrent
Deferred revenue — long term
Contract With Customer Liability Noncurrent
Milestone liabilities
Milestone Liabilities Noncurrent
Deposits from customer
Other Liabilities Noncurrent
Total liabilities
Liabilities
Commitments and contingencies (Note 16)
Commitments And Contingencies
Stockholders' deficit:
Stockholders Equity [Abstract]
Undesignated preferred stock, $0.01 par value — 10,000,000 shares authorized; no shares issued or outstanding at December 31, 2022 and 2021
Preferred Stock Value
Common stock, $0.01 par value — 400,000,000 shares authorized, 263,793,305 and 251,477,562 shares issued and outstanding at December 31, 2022 and 2021, respectively
Common Stock Value
Additional paid-in capital
Additional Paid In Capital Common Stock
Accumulated deficit
Retained Earnings Accumulated Deficit
Total stockholders' deficit
Stockholders Equity
Total liabilities and stockholders' deficit
Liabilities And Stockholders Equity
Gain (loss) on purchase commitments.
Interest expense on financing liability.
Income Statement [Abstract]
Statement [Table]
Statement [Table]
Product and Service
Product Or Service [Axis]
Product and Service
Products And Services [Domain]
Commercial product sales
Product [Member]
Collaborations and services
License And Service [Member]
Royalty collaborations
Royalty [Member]
Statement [Line Items]
Statement [Line Items]
Revenues:
Revenues [Abstract]
Total revenues
Revenue From Contract With Customer Excluding Assessed Tax
Expenses:
Costs And Expenses [Abstract]
Cost of goods sold
Cost Of Goods And Services Sold
Cost of revenue
Cost Of Revenue
In-process research and development
Research And Development In Process
Research and development
Research And Development Expense Excluding Acquired In Process Cost
Selling
Selling Expense
General and administrative
General And Administrative Expense
Asset impairment
Asset Impairment Charges
(Gain) loss on foreign currency translation
Foreign Currency Transaction Gain Loss Realized
Loss on purchase commitments
Gain Loss On Purchase Commitments
Total expenses
Costs And Expenses
Loss from operations
Operating Income Loss
Other (expense) income:
Nonoperating Income Expense [Abstract]
Interest income, net
Investment Income Interest
Interest expense on financing liability
Interest Expense On Financing Liability
Interest expense on notes
Interest Expense Debt
Loss on available-for-sale securities
Debt Securities Available For Sale Gain Loss
Loss on extinguishment of debt
Gains Losses On Extinguishment Of Debt
Other (expense) income
Other Nonoperating Income Expense
Total other expense
Nonoperating Income Expense
Loss before income tax expense
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
Benefit from income taxes
Income Tax Expense Benefit
Net loss
Net Income Loss
Net loss per share - basic
Earnings Per Share Basic
Net loss per share - diluted
Earnings Per Share Diluted
Shares used to compute net loss per share - basic
Weighted Average Number Of Shares Outstanding Basic
Shares used to compute net loss per share - diluted
Weighted Average Number Of Diluted Shares Outstanding
Statement Of Income And Comprehensive Income [Abstract]
Net loss
Other comprehensive loss:
Other Comprehensive Income Loss Net Of Tax Period Increase Decrease [Abstract]
Cumulative translation loss
Other Comprehensive Income Foreign Currency Transaction And Translation Gain Loss Arising During Period Net Of Tax
Comprehensive loss
Comprehensive Income Net Of Tax
Stock issued during period shares stock options and restricted stock units net of forfeitures.
Stock issued during period value stock options and restricted stock units net of forfeitures.
Stock issued during period shares exercise of warrants.
Stock issued during period value exercise of warrants.
Stock issued during period shares market price stock purchase plan.
Stock issued during period value market price stock purchase plan.
Adjustments to additional paid in capital issuance of warrants pursuant to credit facility.
Stock issued during period shares payoff of convertible securities.
Stock issued during period value payoff of convertible securities.
Adjustment to additional paid in capital premium on convertible note.
Issuance of common stock pursuant to a warrant conversion shares.
Issuance of common stock pursuant to a warrant conversion.
Cumulative loss on available-for-sale securities
Statement Of Stockholders Equity [Abstract]
Additional Paid-in Capital
Statement Equity Components [Axis]
Equity Component
Equity Component [Domain]
Common Stock
Common Stock [Member]
Additional Paid-in Capital
Additional Paid In Capital [Member]
Accumulated Other Comprehensive Income (Loss)
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit
Retained Earnings [Member]
Debt Instrument
Debt Instrument [Axis]
Debt Instrument, Name
Debt Instrument Name [Domain]
Convertible notes.
Convertible Notes
Convertible Notes [Member]
Two thousand twenty four convertible notes.
2024 Convertible Notes
Two Thousand Twenty Four Convertible Notes [Member]
Two thousand twenty four convertible note interest.
2024 Convertible Note Interest
Two Thousand Twenty Four Convertible Note Interest [Member]
Senior convertible notes principal.
Senior Convertible Notes Principal
Senior Convertible Notes Principal [Member]
Senior convertible notes interest.
Senior Convertible Notes Interest
Senior Convertible Notes Interest [Member]
Convertible note principal.
Convertible Note Principal
Convertible Note Principal [Member]
Convertible note interest.
Convertible Note Interest
Convertible Note Interest [Member]
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
At-the-market offering.
At-the-market Offering
At The Market Offering [Member]
Related Party
Related Party Transactions By Related Party [Axis]
Related Party
Related Party [Domain]
The mann group llc.
The Mann Group L L C
The Mann Group L L C [Member]
Beginning Balance
Beginning Balance (in shares)
Shares Outstanding
Net issuance of common stock in association with stock options and restricted stock units
Stock Issued During Period Value Stock Options And Restricted Stock Units Net Of Forfeitures
Net issuance of common stock associated with stock options and restricted stock units (in shares)
Stock Issued During Period Shares Stock Options And Restricted Stock Units Net Of Forfeitures
Issuance of common stock pursuant to conversion notes
Stock Issued During Period Value Conversion Of Convertible Securities
Issuance of common stock pursuant to conversion notes (in shares)
Stock Issued During Period Shares Conversion Of Convertible Securities
Issuance of common stock pursuant to payoff of the 2024 convertible note interest
Stock Issued During Period Value Payoff Of Convertible Securities
Issuance of common stock pursuant to payoff of the 2024 convertible note interest (in shares)
Stock Issued During Period Shares Payoff Of Convertible Securities
Issuance of common stock in at-the-market offering/placement
Stock Issued During Period Value New Issues
Issuance of common stock in at-the-market offering/placement (in shares)
Stock Issued During Period Shares New Issues
Issuance cost associated with at-the-market offering/placement
Adjustments To Additional Paid In Capital Stock Issued Issuance Costs
Issuance of common stock under Employee Stock Purchase Plan
Stock Issued During Period Value Employee Stock Purchase Plan
Issuance of common stock under Employee Stock Purchase Plan (in shares)
Stock Issued During Period Shares Employee Stock Purchase Plans
Issuance of common stock from acquisition
Stock Issued During Period Value Acquisitions
Issuance of common stock from acquisition (in shares)
Stock Issued During Period Shares Acquisitions
Stock-based compensation expense
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
Issuance of common stock from the exercise of warrants
Stock Issued During Period Value Exercise Of Warrants
Issuance of common stock from the exercise of warrants (in Share)
Stock Issued During Period Shares Exercise Of Warrants
Premium on Mann Group convertible note
Adjustment To Additional Paid In Capital Premium On Convertible Note
Issuance of common stock from market price stock purchase
Stock Issued During Period Value Market Price Stock Purchase Plan
Issuance of common stock under Market Price Stock Purchase Plan (in shares)
Stock Issued During Period Shares Market Price Stock Purchase Plan
Issuance of warrants pursuant to Midcap Credit Facility
Adjustments To Additional Paid In Capital Issuance Of Warrants Pursuant To Credit Facility
Cumulative translation loss
Issuance of common stock pursuant to a warrant conversion
Issuance Of Common Stock Pursuant To Warrant Conversion
Issuance of common stock pursuant to a warrant conversion (shares)
Issuance Of Common Stock Pursuant To Warrant Conversion Shares
Net loss
Ending Balance
Ending Balance (in shares)
Cumulative loss on available-for-sale securities
Cumulative Loss On Available For Sale Securities
Interest on milestone payment.
Interest expenses on promissory notes.
Increase decrease in recognized loss on purchase commitments.
Increase decrease in operating lease liabilities.
Increase decrease in accrued interest on promissory notes.
Purchase of available-for-sale securities.
Milestone payments.
Proceeds from net issuance of common stock associated with stock options and restricted stock units.
Proceeds from market price stock purchase plan and from employee stock purchase plan.
Payment on financing liability.
Proceeds from the sale-leaseback transaction.
Deposit for the sale-leaseback transaction.
Payment of credit facility prepayment penalty.
Statement Of Cash Flows [Abstract]
At-the-market issuance.
At The Market Issuance
At The Market Issuance [Member]
CASH FLOWS FROM OPERATING ACTIVITIES:
Net Cash Provided By Used In Operating Activities [Abstract]
Net loss
Profit Loss
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Stock-based compensation expense
Share Based Compensation
Depreciation, amortization and accretion
Depreciation And Amortization
Interest expense on financing liability
Interest Expense
Interest on milestone right
Interest On Milestone Payment
Write-off of inventory
Production Related Impairments Or Charges
Interest expense on Mann Group promissory notes
Interest Expense On Promissory Notes
Amortization of right-of-use assets
Operating Lease Right Of Use Asset Amortization Expense
Loss on available-for-sale securities
Loss on extinguishment of debt, net
Asset impairment
Other, net
Other Noncash Income Expense
Changes in operating assets and liabilities:
Increase Decrease In Operating Capital [Abstract]
Accounts receivable, net
Increase Decrease In Accounts Receivable
Inventory
Increase Decrease In Inventories
Prepaid expenses and other current assets
Increase Decrease In Prepaid Deferred Expense And Other Assets
Other assets
Increase Decrease In Other Operating Assets
Accounts payable
Increase Decrease In Accounts Payable
Accrued expenses and other current liabilities
Increase Decrease In Accrued Liabilities And Other Operating Liabilities
Deferred revenue
Increase Decrease In Contract With Customer Liability
Recognized loss on purchase commitments
Increase Decrease In Recognized Loss On Purchase Commitments
Operating lease liabilities
Increase Decrease In Operating Lease Liabilities
Accrued interest on Mann Group promissory notes
Increase Decrease In Accrued Interest On Promissory Notes
Deposits from customer
Increase Decrease In Other Noncurrent Liabilities
Net cash used in operating activities
Net Cash Provided By Used In Operating Activities
CASH FLOWS FROM INVESTING ACTIVITIES:
Net Cash Provided By Used In Investing Activities [Abstract]
Purchase of held-to-maturity debt securities
Payments To Acquire Held To Maturity Securities
Proceeds from maturity of debt securities
Proceeds From Sale And Maturity Of Held To Maturity Securities
Acquisition of V-Go
Payments To Acquire Businesses Net Of Cash Acquired
Purchase of property and equipment
Payments To Acquire Property Plant And Equipment
Purchase of available-for-sale securities
Purchase Of Available For Sale Securities
Proceeds from sale of treasury bills
Proceeds From Sale Of Short Term Investments
Acquisition of in-process research and development, net of cash acquired
Payments To Acquire In Process Research And Development
Net cash provided by (used in) investing activities
Net Cash Provided By Used In Investing Activities
CASH FLOWS FROM FINANCING ACTIVITIES:
Net Cash Provided By Used In Financing Activities [Abstract]
Proceeds from public offering
Proceeds From Issuance Initial Public Offering
Milestone payment
Milestone Payments
Issuance costs associated with the sale-leaseback transaction
Payments Of Stock Issuance Costs
Net issuance of common stock associated with stock options and restricted stock units
Proceeds From Net Issuance Of Common Stock Associated With Stock Options And Restricted Stock Units
Proceeds from market price stock purchase plan and from employee stock purchase plan
Proceeds From Market Price Stock Purchase Plan And From Employee Stock Purchase Plan
Payment on financing liability
Payment On Financing Liability
Issuance of common stock from the exercise of warrants
Proceeds From Warrant Exercises
Proceeds from MidCap credit facility
Proceeds From Lines Of Credit
Proceeds from PPP loan
Proceeds From Issuance Of Long Term Debt
Proceeds from the Senior convertible notes
Proceeds From Convertible Debt
Issuance costs associated with Senior convertible notes
Payments Of Debt Issuance Costs
Proceeds from the sale-leaseback transaction
Proceeds From Sale Leaseback Transaction
Deposit for the sale-leaseback transaction
Deposit For Sale Leaseback Transaction
Principal payments on Mann Group promissory notes
Repayments Of Notes Payable
Payment of MidCap credit facility
Repayments Of Lines Of Credit
Payment of MidCap credit facility prepayment penalty
Payment Of Credit Facility Prepayment Penalty
Net cash provided by financing activities
Net Cash Provided By Used In Financing Activities
NET INCREASE IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD
Reclassification of investments from long-term to current.
Reclassification of convertible notes and interest receivable.
Premium on convertible note.
Payments on debt and interest through common stock issuance.
Addition of right-of-use assets
Right-of-use assets modification.
Common stock issuance to settle employee stock purchase plan liability
Contingent milestone liability.
Common stock issued for acquisition of in-process research and development.
Issuance of warrants associated with Credit Facility.
Receivable from common stock offering.
SUPPLEMENTAL CASH FLOWS DISCLOSURES:
Supplemental Cash Flow Information [Abstract]
Interest paid in cash
Interest Paid Net
NON-CASH INVESTING AND FINANCING ACTIVITIES:
Noncash Investing And Financing Items [Abstract]
Reclassification of investments from long-term to current
Reclassification Of Investments From Long Term To Current
Reclassification of Thirona convertible notes and interest receivable from long-term to current
Reclassification Of Convertible Notes And Interest Receivable
Premium on convertible note
Premium On Convertible Note
Payments on debt and interest through common stock issuance
Payments On Debt And Interest Through Common Stock Issuance
Forgiveness of PPP loan
Debt Instrument Decrease Forgiveness
Addition of right-of-use-asset
Addition Of Right Of Use Assets
Right-of-use asset modification
Right Of Use Assets Modification
Non-cash construction in progress and property and equipment
Capital Expenditures Incurred But Not Yet Paid
Issuance of common stock under Employee Stock Purchase Plan
Common Stock Issuance To Settle Employee Stock Purchase Plan Liability
Contingent milestone liability
Contingent Milestone Liability
Issuance of common stock for acquisition of in-process research and development
Common Stock Issued For Acquisition Of In Process Research And Development
Issuance of warrants associated with the MidCap Credit Facility
Issuance Of Warrants Associated With Credit Facility
Receivable from at-the-market offering
Receivable From Common Stock Offering
Documents Incorporated by Reference
Documents Incorporated By Reference [Text Block]
Accounting Policies [Abstract]
Description of Business
Organization Consolidation And Presentation Of Financial Statements Disclosure And Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Business Combination And Asset Acquisition [Abstract]
Acquisitions
Business Combination Disclosure [Text Block]
Schedule Of Investments [Abstract]
Investments
Investments In Debt And Marketable Equity Securities And Certain Trading Assets Disclosure [Text Block]
Receivables [Abstract]
Accounts Receivable
Financing Receivables [Text Block]
Inventory Disclosure [Abstract]
Inventories
Inventory Disclosure [Text Block]
Property Plant And Equipment [Abstract]
Property and Equipment
Property Plant And Equipment Disclosure [Text Block]
Goodwill And Intangible Assets Disclosure [Abstract]
Goodwill and Other Intangible Asset
Goodwill And Intangible Assets Disclosure [Text Block]
Payables And Accruals [Abstract]
Accrued Expenses and Other Current Liabilities
Accounts Payable And Accrued Liabilities Disclosure [Text Block]
Debt Disclosure [Abstract]
Borrowings
Debt Disclosure [Text Block]
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Collaboration, Licensing and Other Arrangements
Collaborative Arrangement Disclosure [Text Block]
Fair Value Disclosures [Abstract]
Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Equity [Abstract]
Common and Preferred Stock
Stockholders Equity Note Disclosure [Text Block]
Earnings Per Share [Abstract]
Earnings Per Common Share ("EPS")
Earnings Per Share [Text Block]
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Stock Award Plans
Disclosure Of Compensation Related Costs Share Based Payments [Text Block]
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies
Commitments And Contingencies Disclosure [Text Block]
Compensation And Retirement Disclosure [Abstract]
Employee Benefit Plans
Pension And Other Postretirement Benefits Disclosure [Text Block]
Income Tax Disclosure [Abstract]
Income Taxes
Income Tax Disclosure [Text Block]
Business.
Business
Business Policy [Text Block]
Basis of Presentation.
Basis of Presentation
Basis Of Presentation Policy [Text Block]
Principles of Consolidation
Consolidation Policy [Text Block]
Reclassifications
Prior Period Reclassification Adjustment Description
Segment Information
Segment Reporting Policy Policy [Text Block]
Financial Statement Estimates
Use Of Estimates
Revenue Recognition
Revenue Recognition Policy [Text Block]
Revenue from contract with customer from commercial product sales.
Revenue Recognition - Net Revenue - Commercial Product Sales
Revenue From Contract With Customer From Commercial Product Sales Policy [Text Block]
Revenue from contract with customer from collaborations and services.
Revenue Recognition- Net Revenue - Collaborations and Services
Revenue From Contract With Customer From Collaborations And Services Policy [Text Block]
Milestone Payments
Debt Policy [Text Block]
Cost of Goods Sold
Cost Of Sales Policy [Text Block]
Cost of revenues.
Cost of Revenues
Cost Of Revenues Policy [Text Block]
Cash and Cash Equivalents and Restricted Cash
Cash And Cash Equivalents Restricted Cash And Cash Equivalents Policy
Held-to-Maturity Investments
Held To Maturity Securities Purchased Options Price Policy
Available-for-Sale Investment
Available For Sale Securities Purchased Options Price Policy
Concentration of Credit Risk
Concentration Risk Credit Risk
Accounts Receivable and Allowance for Credit Loss
Receivables Trade And Other Accounts Receivable Allowance For Doubtful Accounts Policy
Pre-launch inventory.
Pre Launch Inventory
Pre Launch Inventory Policy [Text Block]
Inventories
Inventory Policy [Text Block]
Property and Equipment
Property Plant And Equipment Policy [Text Block]
Impairment of Long-Lived Assets
Impairment Or Disposal Of Long Lived Assets Policy [Text Block]
Acquistitions
Business Combinations Policy
Goodwill and Other Intangible Assets
Goodwill And Intangible Assets Policy [Text Block]
Loss on purchase commitments.
Recognized Loss on Purchase Commitments
Loss On Purchase Commitments Policy Policy [Text Block]
Milestone rights liability.
Milestone Rights Liability
Milestone Rights Liability Policy [Text Block]
Fair Value of Financial Instruments
Fair Value Of Financial Instruments Policy
Income Taxes
Income Tax Policy [Text Block]
Contingencies
Commitments And Contingencies Policy [Text Block]
Stock-Based Compensation
Compensation Related Costs Policy [Text Block]
Clinical Trial Expense
Clinical Trial Expenses
Clinical Trial Expense Policy [Text Block]
Net Income or (Loss) Per Share of Common Stock
Earnings Per Share Policy [Text Block]
Recently Adopted Accounting Standards
New Accounting Pronouncements Policy Policy [Text Block]
Recently issued accounting standards.
Recently Issued Accounting Standards
Recently Issued Accounting Standards Policy [Text Block]
Summary of Revenue and Cost of Revenue and Goods Sold Generated From Product Sales, Services and Royalties
Disaggregation Of Revenue Table [Text Block]
Schedule Of Business Acquisitions By Acquisition [Table]
Schedule Of Business Acquisitions By Acquisition [Table]
Asset Acquisition
Asset Acquisition [Axis]
Asset Acquisition
Asset Acquisition [Domain]
V-Go.
V-Go
V Go [Member]
Business Acquisition [Line Items]
Business Acquisition [Line Items]
Schedule of Preliminary Purchase Consideration
Asset Acquisition Table [Text Block]
Schedule of Preliminary Amounts of Identifiable Assets Acquired and Liabilities Assumed
Schedule Of Recognized Identified Assets Acquired And Liabilities Assumed Table [Text Block]
Summary of Supplemental Pro Forma Information (Unaudited)
Business Acquisition Pro Forma Information [Text Block]
Schedule of Consideration Paid for IPR&D
Schedule Of Business Acquisitions By Acquisition [Text Block]
Schedule of Contractual Maturities of Held to Maturity Investments
Held To Maturity Securities [Text Block]
Schedule of fair value of assets and financing liability on total investments.
Schedule of Fair Value of Assets and Financing Liability on Total Investments
Schedule Of Fair Value Of Assets And Financing Liability On Total Investments Table [Text Block]
Schedule of Accounts Receivable, Net
Schedule Of Accounts Notes Loans And Financing Receivable [Text Block]
Schedule of activities and ending reserve balance.
Schedule of Activities and Ending Reserve Balance
Schedule Of Activities And Ending Reserve Balance Table [Text Block]
Components of Inventory
Schedule Of Inventory Current Table [Text Block]
Property and Equipment, Net
Property Plant And Equipment [Text Block]
Summary of Other Intangible Asset
Schedule Of Finite Lived Intangible Assets Table [Text Block]
Accrued Expenses and Other Current Liabilities
Schedule Of Accrued Liabilities Table [Text Block]
Discounts and allowances for commercial product sales.
Schedule of Provision for Discounts and Allowances for Commercial Product Sales
Discounts And Allowances For Commercial Product Sales Table [Text Block]
Summary of Carrying Amount of Borrowings
Schedule Of Debt Table [Text Block]
Schedule of Line of Credit Facility Debt and Key Terms
Schedule Of Line Of Credit Facilities [Text Block]
Schedule of Maturities of the Company's Borrowings
Schedule Of Maturities Of Long Term Debt Table [Text Block]
Schedule of amortization of debt issuance cost and debt discount.
Schedule of Amortization of Premium and Accretion of Debt Issuance Costs
Schedule Of Amortization Of Debt Issuance Cost And Debt Discount Table [Text Block]
United Therapeutics Corporation.
United Therapeutics Corporation
United Therapeutics Corporation [Member]
Schedule of Revenue from Collaboration and Services
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions Table [Text Block]
Contract with customer liability.
Schedule of Deferred Revenue Related to Revenue Recognized for Collaborations and Services
Contract With Customer Liability Table [Text Block]
Schedule of Revenue Allocation, Remaining Performance Obligation, Expected Timing of Satisfaction
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction Table [Text Block]
Schedule of Revised anticipated cash flows from transactions allocated performance obligations.
Schedule of Revised Anticipated Cash Flows from Transactions Allocated Performance Obligations
Schedule Of Revised Anticipated Cash Flows From Transactions Allocated Performance Obligations Table [Text Block]
Schedule of effect of modification on transaction price.
Schedule of Effect of Modification on Transaction Price
Schedule Of Effect Of Modification On Transaction Price Table [Text Block]
Fair Value of Financial Instruments
Schedule Of Fair Value Assets And Liabilities Measured On Recurring Basis Table [Text Block]
Components of Basic and Diluted EPS Computations
Schedule Of Earnings Per Share Basic And Diluted Table [Text Block]
Potential Dilutive Securities Outstanding that are Considered Antidilutive
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block]
Stock Based Award Plans
Disclosure Of Share Based Compensation Arrangements By Share Based Payment Award [Text Block]
Stock Based Compensation Expense Recognized in Accompanying Consolidated Statements of Operations by Category
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block]
Assumptions Used to Calculate Fair Value of Employee Stock Options
Schedule Of Share Based Payment Award Employee Stock Purchase Plan Valuation Assumptions Table [Text Block]
Summary of Stock Options Outstanding
Schedule Of Share Based Compensation Stock Options Activity Table [Text Block]
Summary of Restricted Stock Unit Activity
Schedule Of Sharebased Compensation Restricted Stock And Restricted Stock Units Activity Table [Text Block]
Schedule of Lease Term and Discount Rate.
Schedule of Lease Term and Discount Rate
Schedule Of Lease Term And Discount Rate Table [Text Block]
Summary of Lease Information
Lease Cost Table [Text Block]
Summary of Financing Liability Payments
Finance Lease Liability Maturity Table [Text Block]
Remaining Purchase Requirements
Long Term Purchase Commitment [Text Block]
Schedule of Future Minimum Office And Vehicle Lease Payments
Lessee Operating Lease Liability Maturity Table [Text Block]
Loss from Continuing Operations Before Provision for Income Taxes
Schedule Of Income Before Income Tax Domestic And Foreign Table [Text Block]
Provision for Income Taxes
Schedule Of Components Of Income Tax Expense Benefit Table [Text Block]
Components of Net Deferred Tax Assets
Schedule Of Deferred Tax Assets And Liabilities Table [Text Block]
Effective Tax Rate
Schedule Of Effective Income Tax Rate Reconciliation Table [Text Block]
Summary of Positions for which Significant Change in Unrecognized Tax Benefits
Summary Of Positions For Which Significant Change In Unrecognized Tax Benefits Is Reasonably Possible [Text Block]
Debt instrument minimum cash covenant.
Organization, consolidation and presentation of financial statements disclosure.
Organization, Consolidation and Presentation of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Credit Facility
Credit Facility [Axis]
Credit Facility
Credit Facility [Domain]
MidCap Credit Facility.
MidCap Credit Facility
Mid Cap Credit Facility [Member]
Tranche 2
Tranche 2
Tranche Two [Member]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Minimum cash covenant
Debt Instrument Minimum Cash Covenant
Number of operating segment
Number Of Operating Segments
Sales return period.
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Statistical Measurement
Range [Axis]
Statistical Measurement
Range [Member]
Minimum
Minimum [Member]
Maximum
Maximum [Member]
AFREZZA product sales
Convertible promissory note.
Convertible Promissory Note
Convertible Promissory Note [Member]
Thirona Bio, Inc.
Thirona Bio Inc
Thirona Bio Inc [Member]
Long-Lived Assets Held-for-sale by Asset Type
Long Lived Assets Held For Sale By Asset Type [Axis]
Long-Lived Assets Held-for-sale, Name
Long Lived Assets Held For Sale Name [Domain]
Commitment asset.
Commitment Asset
Commitment Asset [Member]
Income Statement Location
Income Statement Location [Axis]
Income Statement Location
Income Statement Location [Domain]
Other Expense
Other Nonoperating Income Expense [Member]
Insulin.
Insulin
Insulin [Member]
Milestone Rights Liability
Milestone Rights Liability
Milestone Rights Liability [Member]
Legal Entity
Legal Entity [Axis]
Entity
Entity [Domain]
Deerfield Management Company L.P.
Deerfield
Deerfield Management Company Lp [Member]
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Sales return right following product expiration in months
Sales Return Period
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction Start Date [Axis]
Remaining performance obligation, Expected timing of satisfaction, period
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction Period1
Revenue From Contract With Customer [Abstract]
Disaggregation Of Revenue [Table]
Disaggregation Of Revenue [Table]
Product sales.
Product Sales
Product Sales [Member]
Services
Service [Member]
Disaggregation Of Revenue [Line Items]
Disaggregation Of Revenue [Line Items]
Total net revenue
Total cost of goods sold and cost of revenue
Operating Expenses
Accretion or amortization
Accretion Amortization Of Discounts And Premiums Investments
Allowance for credit losses on held-to-maturity securities
Debt Securities Held To Maturity Allowance For Credit Loss
Purchase of available-for-sale securities
Maturity date
Investment Maturity Date
Interest rate
Investment Interest Rate
Investment securities
Available For Sale Securities Debt Securities
Available-for-Sale Investment, credit losses
Debt Securities Available For Sale Allowance For Credit Loss
Commitment asset.
Commitment asset
Commitment Asset
Other asset
Other Assets
Asset impairment
Impairment Of Long Lived Assets To Be Disposed Of
Impairments of goodwill
Goodwill Impairment Loss
Impairments of other intangible assets
Impairment Of Intangible Assets Excluding Goodwill
Loss on purchase commitments number of contracts recognized.
Loss on purchase commitments
Purchase Obligation
Loss on purchase commitments, number of new contracts recognized
Loss On Purchase Commitments Number Of Contracts Recognized
Contingent liability remaining payable amount.
Contingent Liability
Contingent liability remain payable
Contingent Liability Remaining Payable Amount
Contingent liability for milestone payments
Contingent Liability
Business Combinations [Abstract]
Business Acquisition
Business Acquisition [Axis]
Business Acquisition, Acquiree
Business Acquisition Acquiree [Domain]
Measurement Input Type
Measurement Input Type [Axis]
Measurement Input Type
Measurement Input Type [Domain]
Risk-Free Rate
Measurement Input Risk Free Interest Rate [Member]
Dividend Yield
Measurement Input Expected Dividend Rate [Member]
Volatility
Measurement Input Price Volatility [Member]
Period
Measurement Input Expected Term [Member]
Dividend Yield
Measurement Input Entity Credit Risk [Member]
QrumPharma Incorporated.
QrumPharma
Qrum Pharma Incorporated [Member]
Global adjusted net sales of products exceeds fifty million.
Global Adjusted Net Sales Of Products Exceeds Fifty Million
Global Adjusted Net Sales Of Products Exceeds Fifty Million [Member]
Adjusted net sales are greater than or equal to two hundred million.
Adjusted Net Sales Are Greater Than Or Equal To Two Hundred Million
Adjusted Net Sales Are Greater Than Or Equal To Two Hundred Million [Member]
Asset acquisition, date of acquisition agreement
Asset Acquisition Date Of Acquisition Agreement
Asset acquisition, effective date of acquisition
Asset Acquisition Effective Date Of Acquisition
Asset acquisition, milestone payment payable.
Annual revenue milestones ranges for milestone payments.
Asset acquisition, up-front consideration
Payments To Acquire Productive Assets
Sales-based milestone payments payable
Asset Acquisition Milestone Payment Payable
Annual revenue milestones ranges for milestone payments
Annual Revenue Milestones Ranges For Milestone Payments
Fair value of consideration:
Asset Acquisition Consideration Transferred [Abstract]
Cash consideration
Fair value of contingent consideration
Asset Acquisition Consideration Transferred Contingent Consideration
Total
Asset Acquisition Consideration Transferred
Goodwill amortization period.
Goodwill amortization period
Goodwill Amortization Period
Business combination recognized identifiable assets acquired and liabilities assumed operating lease right-of-use assets.
Business combination recognized identifiable assets acquired and liabilities assumed current and noncurrent liabilities.
Business combination recognized identifiable assets acquired and liabilities assumed operating lease liability.
Assets:
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Assets [Abstract]
Inventory
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Inventory
Property and equipment
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Property Plant And Equipment
Intangible asset - Developed technology
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Intangible Assets Other Than Goodwill
Operating lease right-of-use assets
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Operating Lease Right Of Use Assets
Total assets
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Assets
Liabilities:
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Liabilities [Abstract]
Liabilities assumed
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Current And Noncurrent Liabilities
Operating lease liability
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Operating Lease Liability
Total liabilities
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Liabilities
Net assets acquired
Business Combination Recognized Identifiable Assets Acquired Goodwill And Liabilities Assumed Net
Incremental borrowing rate
Operating Lease Weighted Average Discount Rate Percent
Measurement inputs
Business Combination Contingent Consideration Liability Measurement Input
Acquisition-related costs
Business Combination Acquisition Related Costs
Net revenue
Business Combination Pro Forma Information Revenue Of Acquiree Since Acquisition Date Actual
Loss from operations
Business Combination Pro Forma Information Earnings Or Loss Of Acquiree Since Acquisition Date Actual
Business Acquisition Pro Forma Information [Abstract]
Net revenue
Business Acquisitions Pro Forma Revenue
Net loss
Business Acquisitions Pro Forma Net Income Loss
Net loss per share - basic
Business Acquisition Pro Forma Earnings Per Share Basic
Net loss per share - diluted
Business Acquisition Pro Forma Earnings Per Share Diluted
Acquisition date
Business Acquisition Effective Date Of Acquisition1
Business acquisition, repayment of debt.
Cash consideration
Payments To Acquire Businesses Gross
Stock consideration (3,067,179 shares at $3.01 per share)
Business Combination Consideration Transferred Equity Interests Issued And Issuable
Transaction costs
Payments For Merger Related Costs
Repayment of debt
Business Acquisition Repayment Of Debt
Liabilities assumed
Business Combination Consideration Transferred Liabilities Incurred
Cash acquired
Cash Acquired From Acquisition
Total consideration paid for IPR&D
Business Combination Consideration Transferred1
Number of common stock issued
Business Acquisition Equity Interests Issued Or Issuable Number Of Shares Issued
Business acquisition, share price
Business Acquisition Share Price
Business combination accumulated cost.
Business acquisition, total accumulated cost
Business Combination Accumulated Cost
Percentage of royalty payment on net sales.
Global adjusted net sales of products reference amount for royalty percentage.
Royalty payment in each of the calendar years
Percentage Of Royalty Payment On Net Sales
Global adjusted net sales of products, reference amount for royalty percentage.
Global Adjusted Net Sales Of Products Reference Amount For Royalty Percentage
Schedule Of Investments [Table]
Schedule Of Investments [Table]
Cash and Cash Equivalents
Cash And Cash Equivalents [Axis]
Cash and Cash Equivalents
Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member]
Money Market Funds
Money Market Funds [Member]
Debt Security Category
Information By Category Of Debt Security [Axis]
Other than Temporary Impairment, Credit Losses Recognized in Earnings, Categories of Investments
Other Than Temporary Impairment Credit Losses Recognized In Earnings Categories Of Investments [Domain]
Held-to-Maturity Investments
Heldtomaturity Securities [Member]
Schedule Of Investments [Line Items]
Schedule Of Investments [Line Items]
Restricted cash
Restricted Cash Current
Investments
Investments
Held To Maturity Securities Debt Maturities [Abstract]
Amortized cost basis, due in one year or less
Held To Maturity Securities Debt Maturities Within One Year Net Carrying Amount
Amortized cost basis due after one year through five years
Held To Maturity Securities Debt Maturities After One Through Five Years Net Carrying Amount
Amortized cost basis, total
Held To Maturity Securities Debt Maturities Single Maturity Date Amortized Cost Basis
Aggregate fair value, due in one year or less
Held To Maturity Securities Debt Maturities Within One Year Fair Value
Aggregate fair value, due after one year through five years
Held To Maturity Securities Debt Maturities After One Through Five Years Fair Value
Aggregate fair value, total
Held To Maturity Securities Debt Maturities Single Maturity Date Fair Value
Schedule Of Held To Maturity Securities [Table]
Schedule Of Held To Maturity Securities [Table]
Short-Term Debt, Type
Short Term Debt Type [Axis]
Short-Term Debt, Type
Short Term Debt Type [Domain]
Due in one year or less.
Due in One Year or Less
Due In One Year Or Less [Member]
Schedule Of Held To Maturity Securities [Line Items]
Schedule Of Held To Maturity Securities [Line Items]
Fair value of financial instruments.
Fair Value of Financial Instruments [Table]
Fair Value Of Financial Instruments [Table]
Fair Value Of Financial Instruments [Table]
Amortized cost.
Amortized Cost
Amortized Cost [Member]
Gross unrealized holding losses.
Gross Unrealized Holding Losses
Gross Unrealized Holding Losses [Member]
Estimated fair value.
Estimated Fair Value
Estimated Fair Value [Member]
Commercial Bonds and Paper
Commercial Paper [Member]
U.S. Treasuries
U S Treasury Securities [Member]
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
Fair Value, Inputs, Level 2
Fair Value Inputs Level2 [Member]
Fair Value, Inputs, Level 1
Fair Value Inputs Level1 [Member]
Fair Value Of Financial Instruments [Line Items]
Fair Value Of Financial Instruments [Line Items]
Total cash equivalents and investments
Cash Equivalents And Investments
Less cash equivalents
Cash Equivalents At Carrying Value
Total Investments
Accrued interest receivable.
Amount receivable on matured investment.
Accrued interest receivable
Accrued Interest Receivable
Amount receivable on matured investment
Amount Receivable On Matured Investment
Schedule Of Accounts Notes Loans And Financing Receivable [Table]
Schedule Of Accounts Notes Loans And Financing Receivable [Table]
Accounts Receivable [Line Items]
Accounts Notes And Loans Receivable [Line Items]
Accounts receivable, gross
Accounts Receivable Gross Current
Wholesaler distribution fees and prompt pay discounts
Wholesaler Distribution Fees And Prompt Pay Discounts
Reserve for returns
Reserve For Returns
Total accounts receivable, net
Allowance for credit losses
Allowance For Doubtful Accounts Receivable Current
Number of wholesale distributors.
Percentage of accounts receivable from major customers.
Percentage of sales from major customers.
Number of wholesale distributors
Number Of Wholesale Distributors
Percentage of accounts receivable from major wholesale distributors
Percentage Of Accounts Receivable From Major Customers
Percentage of gross sales from major wholesale distributors
Percentage Of Sales From Major Customers
Percentage of collaborations and services net accounts receivables.
Percentage of revenue from major customers collaborations and services.
Allowance for credit losses for accounts receivable
Percentage of collaborations and services net accounts receivables
Percentage Of Collaborations And Services Net Accounts Receivables
Percentage of revenue from major customers collaborations and services
Percentage Of Revenue From Major Customers Collaborations And Services
Prompt pay discount reserve allowance for wholesale distribution fees and accounts receivables return reserve.
Prompt pay discount reserve allowance for wholesale distribution fees and accounts receivables return reserve provisions.
Prompt pay discount reserve allowance for wholesale distribution fees and accounts receivables return reserve deductions.
Reserve balance.
Reserve Balance [Abstract]
Beginning balance
Prompt Pay Discount Reserve Allowance For Wholesale Distribution Fees And Accounts Receivables Return Reserve
Provisions
Prompt Pay Discount Reserve Allowance For Wholesale Distribution Fees And Accounts Receivables Return Reserve Provisions
Deductions
Prompt Pay Discount Reserve Allowance For Wholesale Distribution Fees And Accounts Receivables Return Reserve Deductions
Ending balance
Raw materials
Inventory Raw Materials Net Of Reserves
Work-in-process
Inventory Work In Process Net Of Reserves
Finished goods
Inventory Finished Goods Net Of Reserves
Total inventory
Inventory Current [Table]
Inventory Current [Table]
Inventory
Public Utilities Inventory [Axis]
Inventory
Public Utilities Inventory Type [Domain]
pre-launch inventory.
Pre-launch Inventory
Pre Launch Inventory [Member]
Agreement with a retail pharmacy.
Agreement With Retail Pharmacy
Agreement With Retail Pharmacy [Member]
Inventory [Line Items]
Inventory [Line Items]
Raw materials inventory
Inventory Raw Materials
Inventory write-offs
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Long-Lived Tangible Asset
Property Plant And Equipment By Type [Axis]
Long-Lived Tangible Asset
Property Plant And Equipment Type [Domain]
Land
Land [Member]
Buildings
Building [Member]
Building Improvements
Building Improvements [Member]
Machinery and Equipment
Machinery And Equipment [Member]
Furniture, fixtures and office equipment.
Furniture, fixtures and office equipment
Furniture Fixtures And Office Equipment [Member]
Computer equipment and software.
Computer Equipment and Software
Computer Equipment And Software [Member]
Construction in Progress
Construction In Progress [Member]
Property Plant And Equipment [Line Items]
Property Plant And Equipment [Line Items]
Property and equipment - gross
Property Plant And Equipment Gross
Less accumulated depreciation
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Total property and equipment, net
Estimated Useful Life (Years)
Property Plant And Equipment Useful Life
UT Equipment.
U T Equipment
U T Equipment [Member]
Construction in Progress, Gross
Construction In Progress Gross
Proceeds from related party
Proceeds From Related Party Debt
Manufacturing equipments and computer hardware.
Manufacturing Equipment and Computer Hardware
Manufacturing Equipments And Computer Hardware [Member]
Manufacturing Equipment, Computer Hardware and Software, Computer Equipment, Lab Equipment, and Building Improvements.
Manufacturing Equipment, Computer Hardware and Software, Computer Equipment, Lab Equipment, and Building Improvements
Manufacturing Equipment Computer Hardware And Software Computer Equipment Lab Equipment And Building Improvements [Member]
Counterparty Name
Counterparty Name [Axis]
Counterparty Name
Repurchase Agreement Counterparty Name [Domain]
1 Casper, LLC.
Casper L L C
Casper L L C [Member]
Depreciation Expense
Depreciation
Amount of divestiture of long-lived
Property Plant And Equipment Disposals
Sale leaseback transaction, lease agreement periods.
Sale price
Proceeds From Sale Of Real Estate
Sale leaseback transaction, lease agreement period.
Sale Leaseback Transaction Lease Agreement Periods
Sale leaseback transaction, date
Sale Leaseback Transaction Date
2023
Finite Lived Intangible Assets Amortization Expense Next Twelve Months
2024
Finite Lived Intangible Assets Amortization Expense Year Two
2025
Finite Lived Intangible Assets Amortization Expense Year Three
2026
Finite Lived Intangible Assets Amortization Expense Year Four
2027
Finite Lived Intangible Assets Amortization Expense Year Five
After 2027
Finite Lived Intangible Assets Amortization Expense After Year Five
Schedule Of Finite Lived Intangible Assets [Table]
Schedule Of Finite Lived Intangible Assets [Table]
Finite-Lived Intangible Assets by Major Class
Finite Lived Intangible Assets By Major Class [Axis]
Finite-Lived Intangible Assets, Major Class Name
Finite Lived Intangible Assets Major Class Name [Domain]
Developed Technology
Developed Technology Rights [Member]
Finite Lived Intangible Assets [Line Items]
Finite Lived Intangible Assets [Line Items]
Estimated Useful Life (Years)
Finite Lived Intangible Asset Useful Life
Cost
Finite Lived Intangible Assets Gross
Accumulated Amortization
Finite Lived Intangible Assets Accumulated Amortization
Net Book Value
Finite Lived Intangible Assets Net
Customer Discounts And Allowances
Returns reserve for acquired product.
Current portion of milestone right liability.
Retail inventory purchase.
Salary and related expenses
Employee Related Liabilities Current
Discounts and allowances for commercial product sales
Customer Discounts And Allowances
Returns reserve for acquired product
Returns Reserve For Acquired Product
Professional fees
Accrued Professional Fees Current
Deferred lease liability
Direct Financing Lease Deferred Selling Profit
Current portion of milestone rights liability
Current Portion Of Milestone Right Liability
Accrued interest
Interest Payable Current
Retail inventory purchase
Retail Inventory Purchase
Danbury facility buildout
Construction Payable Current
Other
Other Accrued Liabilities Current
Accrued expenses and other current liabilities
Discounts and allowances for commercial product sales.
Discounts and allowances for commercial product sales provisions.
Discounts and allowances for commercial product sales deductions.
Discounts and allowances for commercial product sales balances from acquisition.
Discounts and allowances for commercial product sales.
Discounts and allowances for commercial product sales:
Discounts And Allowances For Commercial Product Sales [Abstract]
Beginning balance
Discounts And Allowances For Commercial Product Sales
Provisions
Discounts And Allowances For Commercial Product Sales Provisions
Deductions
Discounts And Allowances For Commercial Product Sales Deductions
V-Go opening balance sheet
Discounts And Allowances For Commercial Product Sales Balances From Acquisition
Ending balance
Debt Instrument [Table]
Debt Instrument [Table]
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Senior convertible notes
Senior Notes
Mann Group promissory notes
Notes Payable Related Parties Noncurrent
Credit Facility
Line Of Credit
Total debt — net carrying amount
Long Term Debt
Debt premium recognized in additional paid-in capital.
Promissory notes.
Promissory Notes
Promissory Notes [Member]
Debt premium recognized in additional paid-in capital
Debt Premium Recognized In Additional Paid In Capital
Debt instrument maturity month and year.
Accrued paid in kind interest.
Debt instrument floor rate.
Debt instrument cap interest rate.
Variable Rate
Variable Rate [Axis]
Variable Rate
Variable Rate [Domain]
SOFR
Secured Overnight Financing Rate Sofr Overnight Index Swap Rate [Member]
Long-Term Debt, Type
Longterm Debt Type [Axis]
Long-Term Debt, Type
Longterm Debt Type [Domain]
Senior Convertible Notes
Senior Notes [Member]
Amount Due
Debt Instrument Face Amount
Accrued interest paid-in-kind
Accrued Paid In Kind Interest
Annual interest rate
Debt Instrument Interest Rate Stated Percentage
Interest rate floor
Debt Instrument Floor Rate
Interest rate cap
Debt Instrument Cap Interest Rate
Maturity date
Debt Instrument Maturity Month And Year
Conversion price
Debt Instrument Convertible Conversion Price1
LIBOR
London Interbank Offered Rate L I B O R [Member]
Non-convertible promissory note.
Non Convertible Promissory Note
Non Convertible Promissory Note [Member]
Prior to midcap credit facility amendment.
Prior To Midcap Credit Facility Amendment
Prior To Midcap Credit Facility Amendment [Member]
prior to the first amendment.
Prior to First Amendment
Prior To First Amendment [Member]
Prepayment of principal balance
Early Repayment Of Senior Debt
2023
Long Term Debt Maturities Repayments Of Principal In Next Twelve Months
2024
Long Term Debt Maturities Repayments Of Principal In Year Two
2025
Long Term Debt Maturities Repayments Of Principal In Year Three
2026
Long Term Debt Maturities Repayments Of Principal In Year Four
Total principal payments
Debt Instrument Carrying Amount
Unamortized discount
Debt Instrument Unamortized Discount
Debt issuance costs
Deferred Finance Costs Net
Private Placement
Private Placement [Member]
Principal amount
Number of trading days.
Consecutive trading days.
Debt instrument convertible conversion price percentage.
Principal amount per share.
Measurement period percentage.
Maturity date
Debt Instrument Maturity Date
Number of trading days
Number Of Trading Days
Consecutive trading days
Consecutive Trading Days
Conversion price percentage
Debt Instrument Convertible Conversion Price Percentage
Principal amount per share
Principal Amount Per Share
Measurement period percentage
Measurement Period Percentage
Debt Instrument initial conversion price of premium percentage.
Conversion price
Initial conversion price of premium percentage
Debt Instrument Initial Conversion Price Of Premium Percentage
No of convertible shares
Debt Instrument Convertible Conversion Ratio1
Debt instrument outstanding principal amount redeemed.
Redemption period start date
Debt Instrument Redemption Period Start Date
Redemption price percentage
Debt Instrument Redemption Price Percentage Of Principal Amount Redeemed
Outstanding principal amount redeemed
Debt Instrument Outstanding Principal Amount Redeemed
Sinking fund
Debt Instrument Sinking Fund Payment
Debt instrument redemption description
Debt Instrument Redemption Description
Percentage of repurchase price
Debt Instrument Redemption Price Percentage
Debt default, description
Default Longterm Debt Description Of Violation Or Event Of Default
Proceeds from offering after deducting initial purchasers discounts and commissions and estimated offering expenses payable
Unamortized debt issuance cost
Unamortized Debt Issuance Expense
Prepayment of secured lines of credit.
Tranche one.
Tranche 1
Tranche One [Member]
Tranche 3.
Tranche 3
Tranche Three [Member]
Debt Instrument, Redemption, Period
Debt Instrument Redemption Period [Axis]
Debt Instrument, Redemption, Period
Debt Instrument Redemption Period [Domain]
On or After April 23, 2022 Through and Including April 22, 2023
Debt Instrument Redemption Period Two [Member]
On or Prior to April 22, 2022
Debt Instrument Redemption Period One [Member]
On or After April 23, 2023 Through Maturity Date
Debt Instrument Redemption Period Three [Member]
Advance of borrowing
Proceeds From Secured Lines Of Credit
Prepaid of borrowing
Prepayment Of Secured Lines Of Credit
Amount available under credit facility
Line Of Credit Facility Remaining Borrowing Capacity
Debt instrument advance available date.
Debt instrument extended interest-only date.
Maximum value of additional investment limit.
Debt instrument minimum unrestricted cash and short-term investments.
Debt Instrument unamortized prepayment penalty.
Debt instrument advance available date
Debt Instrument Advance Available Date
Debt instrument extended interest-only date
Debt Instrument Extended Interest Only Date
Debt instrument payment term description
Debt Instrument Frequency Of Periodic Payment
Maximum value of additional investment limit
Maximum Value Of Additional Investment Limit
Debt instrument minimum unrestricted cash and short-term investments
Debt Instrument Minimum Unrestricted Cash And Short Term Investments
Principal prepayment against outstanding term loans
Repayments Of Long Term Lines Of Credit
Debt instrument, prepayment penalty
Payments Of Debt Extinguishment Costs
Unamortized debt discount
Debt Instrument unamortized prepayment penalty.
Debt Instrument Unamortized Prepayment Penalty
Early termination fees percentage.
Debt instrument payment number of equal monthly installments.
Line of credit facility principal payment start date.
Debt Instrument, Interest Rate, Effective Percentage
Debt Instrument Interest Rate Effective Percentage
Debt Instrument, Basis Spread on Variable Rate
Debt Instrument Basis Spread On Variable Rate1
Debt Instrument Payment Number of Equal Monthly Installments
Debt Instrument Payment Number Of Equal Monthly Installments
Line Of Credit Facility Principal Payment Start Date
Line Of Credit Facility Principal Payment Start Date
Early Termination Fees Percentage
Early Termination Fees Percentage
Interest on loans increased, percentage
Debt Instrument Interest Rate Increase Decrease
Term loan advance percentage of amount drawdown.
Term loan advance percentage of amount drawdown
Term Loan Advance Percentage Of Amount Drawdown
Warrants to purchase of common stock
Class Of Warrant Or Right Number Of Securities Called By Each Warrant Or Right
Exercise price of warrants
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
Collaborative Arrangement and Arrangement Other than Collaborative
Type Of Arrangement [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Arrangements And Nonarrangement Transactions [Member]
Privately-negotiated exchange agreement.
Privately Negotiated Exchange Agreement
Privately Negotiated Exchange Agreement [Member]
Related Party Transaction
Related Party Transaction [Axis]
Related Party Transaction
Related Party Transaction [Domain]
Loan arrangement.
Loan Arrangement
Loan Arrangement [Member]
Non convertible note.
Non-Convertible Note
Non Convertible Note [Member]
New loan arrangement.
New Loan Arrangement
New Loan Arrangement [Member]
Debt Conversion Description
Debt Conversion By Unique Description [Axis]
Debt Conversion, Name
Debt Conversion Name [Domain]
Accrued interest.
Accrued Interest
Accrued Interest [Member]
Common stock price per share
Share Price
Senior notes, effective interest rate
Debt instrument, date of first required interest payment
Debt Instrument Date Of First Required Payment1
Debt instrument fair value in excess of face amount.
Debt instrument fair value in excess of face amount
Debt Instrument Fair Value In Excess Of Face Amount
Common stock issued to pay interest.
Debt issuance amount
Debt Conversion Converted Instrument Amount1
Conversion of notes to common shares, shares
Debt Conversion Converted Instrument Shares Issued1
Interest Expense Debt
Common stock issued to pay interest
Common Stock Issued To Pay Interest
Paycheck Protection Program, CARES Act.
PPP Loan
Paycheck Protection Program C A R E S Act [Member]
Proceeds from Issuance of Long-term Debt
Amortization of debt discount.
Amortization of debt discount
Amortization Of Debt Discount
Amortization of debt issuance cost
Amortization Of Financing Costs And Discounts
Milestone rights liabilities current and noncurrent.
Payment for milestone rights liabilities.
Milestone rights liability current.
Barings Global milestone rights.
Barings Global Milestone Rights
Barings Global Milestone Rights [Member]
Remaining milestone rights liability
Milestone Rights Liabilities Current And Noncurrent
Payment for milestone liability
Payment For Milestone Rights Liabilities
Milestone rights liability, current
Milestone Rights Liability Current
Accrued expenses and other current liabilities
Accrued Liabilities And Other Liabilities
Related Party Transactions [Abstract]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
License agreement.
License Agreement
License Agreement [Member]
commercial supply agreement.
Commercial Supply Agreement
Commercial Supply Agreement [Member]
Co-promotion agreement.
Co-Promotion Agreement
Co Promotion Agreement [Member]
Collaboration and license agreement.
Collaboration and License Agreement
Collaboration And License Agreement [Member]
License and Distribution Agreement
License And Distribution Agreement [Member]
Other agreement.
Other
Other Agreement [Member]
Research agreement.
Research Agreement
Research Agreement [Member]
Vertice Pharma LLC.
Vertice Pharma LLC
Vertice Pharma L L C [Member]
Receptor Life Science Inc.
Receptor CLA
Receptor Life Science Inc [Member]
Cipla Ltd.
Cipla Ltd
Cipla Ltd [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue from collaborations and services
Contract with customer liability additions.
Contract with customer liability collaborations and services revenue.
Beginning balance
Contract With Customer Liability
Additions
Contract With Customer Liability Additions
Revenue — collaborations and services
Contract With Customer Liability Collaborations And Services Revenue
Ending balance
Royalties.
Royalties Arrangement
Royalties Arrangement [Member]
Total revenue from UT
Additional option exercise and development milestone payments to be received.
Upfront payment received.
Milestone payment received.
Contract with Customer, Duration
Contract With Customer Duration [Axis]
Contract with Customer, Duration
Contract With Customer Duration [Domain]
Clinical Supplies.
Clinical Supplies
Clinical Supplies [Member]
Tyvaso DPI.
Tyvaso DPI
Tyvaso D P I [Member]
Manufacturing services.
Manufacturing Services
Manufacturing Services [Member]
Next-gen research and development services.
Next-Gen R&D Services
Next Gen Research And Development Services [Member]
Loss Contingency Nature
Loss Contingencies By Nature Of Contingency [Axis]
Loss Contingency, Nature
Loss Contingency Nature [Domain]
Transaction price for the contractual obligations.
Transaction Price For The Contractual Obligations
Transaction Price For The Contractual Obligations [Member]
Transaction price for the performance obligations.
Transaction Price For The Performance Obligations
Transaction Price For The Performance Obligations [Member]
Commercialization and continuous improvement activities.
Commercialization And Continuous Improvement Activities
Commercialization And Continuous Improvement Activities [Member]
Amendment to co-promotion agreement..
Amendment to Co Promotion Agreement
Amendment To Co Promotion Agreement [Member]
Supply and distribution agreement.
Supply and Distribution Agreement
Supply And Distribution Agreement [Member]
Biomm S.A.
Biomm
Biomm S A [Member]
Upfront payment received
Upfront Payment Received
Milestone Payment Received
Milestone Payment Received
Additional option exercise and development milestone payments to be receive
Additional Option Exercise And Development Milestone Payments To Be Received
Total transaction price
Revenue Remaining Performance Obligation
Research and development services and license.
R&D Services and License
Research And Development Services And License [Member]
Timing of Transfer of Good or Service
Timing Of Transfer Of Good Or Service [Axis]
Timing of Transfer of Good or Service
Timing Of Transfer Of Good Or Service [Domain]
Over Time
Transferred Over Time [Member]
Pre-commercial services.
Pre-Commercial Services
Pre Commercial Services [Member]
Facility expansion services.
Facility Expansion Services
Facility Expansion Services [Member]
Point In Time
Transferred At Point In Time [Member]
Allocation of Price
Revenue Remaining Performance Obligation Percentage
Progress Measure
Revenue Performance Obligation Satisfied Over Time Method Used Description
Recognition Period
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction Explanation
Revenue remaining performance obligation anticipated cash flow.
Total anticipated cash flows
Revenue Remaining Performance Obligation Anticipated Cash Flow
Anticipated Revenue Allocation
Revenue recognized during period
Contract With Customer Liability Revenue Recognized
Agreement amendment description.
Amendment description
Agreement Amendment Description
Allocated transaction price.
Allocated transaction price
Allocated Transaction Price
Deferred revenue
Deferred revenue - non-current
Funding for capital improvements
Payments For Capital Improvements
Funding for development of alternative manufacturing processes
Payments To Acquire Other Productive Assets
Percentage of modification of previously fixed consideration.
Percentage of modification of previously fixed consideration
Percentage Of Modification Of Previously Fixed Consideration
Deferred revenue recognition period
Reserve for allowance for doubtful accounts
Contract With Customer Receivable Allowance For Credit Loss
Impairment on contract assets related to variable consideration
Capitalized Contract Cost Impairment Loss
Date of agreement initiation for marketing and distribution.
Marketing and distribution agreement date
Date Of Agreement Initiation For Marketing And Distribution
Fair Value, Inputs, Level 3
Fair Value Inputs Level3 [Member]
Fair Value By Balance Sheet Grouping [Table]
Fair Value By Balance Sheet Grouping [Table]
Measurement Basis
Fair Value By Measurement Basis [Axis]
Fair Value Disclosure Item Amounts [Default]
Portion At Fair Value Fair Value Disclosure [Member]
Fair Value Measurement
Fair Value Disclosure Item Amounts [Domain]
Carrying Amount
Carrying Reported Amount Fair Value Disclosure [Member]
Estimate of Fair Value Measurement
Estimate Of Fair Value Fair Value Disclosure [Member]
Senior convertible notes
Mann group convertible note.
Mann Group Convertible Note
Mann Group Convertible Note [Member]
Contingent milestone liability.
Contingent Milestone Liability
Contingent Milestone Liability [Member]
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Financial liabilities:
Financial Liabilities Fair Value Disclosure [Abstract]
Total financial liabilities fair value
Financial Liabilities Fair Value Disclosure
Note payable, percentage of interest rate change.
Debt instrument measurement input after change.
Substantial premium based on fair value post modification recognized as additional paid-in capital.
Note payable, percentage of hypothetical yield
Debt Instrument Measurement Input After Change
Note payable, percentage of volatility
Debt Instrument Measurement Input
Note payable, percentage of interest rate increases (decreases)
Note Payable Percentage Of Interest Rate Change
Financial liabilities fair value
Substantial premium based on fair value post modification recognized as additional paid-in capital
Substantial Premium Based On Fair Value Post Modification Recognized As Additional Paid In Capital
Financing liability, long term
Financing liability, short term
Schedule Of Stock By Class [Table]
Schedule Of Stock By Class [Table]
Contolled equity offering sales agreement.
Contolled Equity Offering Sales Agreement
Contolled Equity Offering Sales Agreement [Member]
At market issuance sales agreement.
At Market Issuance Sales Agreement
At Market Issuance Sales Agreement [Member]
Cantor fitzgerald.
Cantor Fitzgerald
Cantor Fitzgerald [Member]
Weighted Average
Weighted Average [Member]
June two thousand twenty note.
June 2020 Note
June Two Thousand Twenty Note [Member]
December two thousand twenty note.
December 2020 Note
December Two Thousand Twenty Note [Member]
Underwriting agreement.
Underwriting Agreement
Underwriting Agreement [Member]
Class of Stock [Line Items]
Class Of Stock [Line Items]
Common stock, shares authorized
Amount of net proceeds from issuance of securities
Proceeds From Issuance Of Common Stock
Stock purchase agreements date
Sale Of Stock Transaction Date
Number of shares sold during the period
Exchange price per share
Shares Issued Price Per Share
Issuance of common stock to note holders
Remaining Warrants Available for Purchase.
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights
Class of Warrant or Right, Outstanding
Class Of Warrant Or Right Outstanding
Remaining Warrants Available for Purchase
Remaining Warrants Available For Purchase
Debt conversion converted instrument shares issued for accrued interest of notes.
Debt conversion converted instrument accrued interest of notes value.
Conversion of notes accrued interest to common shares, value
Debt Conversion Converted Instrument Accrued Interest Of Notes Value
Conversion of notes accrued interest to common shares
Debt Conversion Converted Instrument Shares Issued For Accrued Interest Of Notes
Market price stock purchase plan.
Proceeds from stock purchase plans
Proceeds From Stock Plans
Market price stock purchase plan
Market Price Stock Purchase Plan
Earning per share basic and diluted.
EPS — basic and diluted:
Earning Per Share Basic And Diluted [Abstract]
Net loss (numerator)
Weighted average common shares (denominator)
Net loss per share, Basic
Net loss per share, Diluted
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Senior convertible notes.
Senior Convertible Notes
Senior Convertible Notes [Member]
Common stock options and performance based stock option awards.
Common Stock Options and PNQs
Common Stock Options And Performance Based Stock Option Awards [Member]
Warrants associated with Midcap Credit Facility.
Warrants Associated with MidCap Credit Facility
Warrants Associated With Midcap Credit Facility [Member]
Employee stock purchase plan.
Employee Stock Purchase Plan
Employee Stock Purchase Plan [Member]
Restricted stock units and market restricted stock units.
RSUs and Market RSUs
Restricted Stock Units And Market Restricted Stock Units [Member]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Anti-dilutive securities excluded from computation of earnings per share
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
Share based compensation arrangement by share based payment award number of shares available for grant increased by shares.
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Plan Name
Plan Name [Axis]
Plan Name
Plan Name [Domain]
Equity incentive plan twenty eighteen.
2018 Equity Incentive Plan
Equity Incentive Plan Twenty Eighteen [Member]
Equity incentive plan twenty thirteen.
2013 Equity Incentive Plan
Equity Incentive Plan Twenty Thirteen [Member]
Award Type
Award Type [Axis]
Award Type
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
Stock Options
Employee Stock Option [Member]
Restricted Stock
Restricted Stock [Member]
Vesting
Vesting [Axis]
Vesting
Vesting [Domain]
Tranche One
Share Based Compensation Award Tranche One [Member]
RSUs
Restricted Stock Units R S U [Member]
Group One.
Less than 25th Percentile
Group One [Member]
Group Two.
25th Percentile
Group Two [Member]
Group Three.
50th Percentile
Group Three [Member]
Group Four.
75th Percentile
Group Four [Member]
Group Five.
90th Percentile or Higher
Group Five [Member]
Restricted stock units and options.
RSUs and Options
Restricted Stock Units And Options [Member]
Performance-based Stock Options
Performance Shares [Member]
Employee stock options and performance based options.
Options and Performance-based Options
Employee Stock Options And Performance Based Options [Member]
Title of Individual
Title Of Individual [Axis]
Title of Individual
Title Of Individual With Relationship To Entity [Domain]
Employee [Member]
Employee
Employee [Member]
ESPP
Employee Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity incentive plan, shares
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Authorized
Equity incentive plan, number of shares available for grant increased by shares
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Increased By Shares
Exercise or strike price of fair market value of underlying common stock on date of grant reacquired or withheld.
Exercise or strike price of fair market value of underlying common stock on date of grant reacquired or withheld
Exercise Or Strike Price Of Fair Market Value Of Underlying Common Stock On Date Of Grant Reacquired Or Withheld
Vesting period
Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period
Vesting period
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1
Vesting rights percentage
Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage
Share based compensation arrangement by share based payment award vesting date.
Percentile rank of shareholder return of stock.
Share based compensation arrangement by share based payment award target percentage.
Grant date fair value per share
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
Vesting date
Share Based Compensation Arrangement By Share Based Payment Award Vesting Date
Risk-free interest rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
Volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
Dividend yield
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Percentile
Percentile Rank Of Shareholder Return Of Stock
Percent of target
Share Based Compensation Arrangement By Share Based Payment Award Target Percentage
Two Thousand Four Equity Incentive Plan [Member]
2004 Equity Incentive Plan
Two Thousand Four Equity Incentive Plan [Member]
Outstanding Options
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Outstanding Restricted Stock Units
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
Shares Available for Future Issuance
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
Stock-based compensation
Allocated Share Based Compensation Expense
Cost of Goods Sold
Cost Of Sales [Member]
Research and development
Research And Development Expense [Member]
Cost of revenue collaborations and services.
Cost of Revenue - Collaborations and Services
Cost Of Revenue Collaborations And Services [Member]
Selling
Selling And Marketing Expense [Member]
General and administrative
General And Administrative Expense [Member]
Share based compensation
Options issued or granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period
Transfers From (To) Parent [Abstract]
Transfers From To Parent [Abstract]
Minimum
Maximum
Risk free interest rate, minimum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
Risk free interest rate, maximum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
Expected lives
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
Volatility, minimum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
Volatility, maximum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
Number of Shares
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Roll Forward
Outstanding at January 1, 2022
Granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Exercised
Stock Issued During Period Shares Stock Options Exercised
Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
Expired
Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period
Outstanding at December 31, 2022
Exercisable at December 31, 2022
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Weighted Average Exercise Price per Share
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Rollforward
Outstanding at January 1, 2022
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Granted
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Exercised
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
Forfeited
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
Expired
Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price
Outstanding at December 31, 2022
Exercisable at December 31, 2022
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
Weighted Average Remaining Contractual Term (Years)
Share Based Compensation Arrangement By Share Based Payment Award Options Additional Disclosures [Abstract]
Outstanding
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Exercisable at December 31, 2022
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Exercisable Weighted Average Remaining Contractual Term1
Share-based Compensation Arrangement by Share-based Payment Award, Options, Aggregate Intrinsic Value [Abstract]
Aggregate Intrinsic Value
Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract]
Aggregate Intrinsic Value, Outstanding
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
Exercisable at December 31, 2022
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
Weighted average grant date fair value of the stock options granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
Weighted average grant date fair value of the stock options vested
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Weighted Average Grant Date Fair Value
Total intrinsic value of options exercised
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
Cash received from the exercise of options
Proceeds From Stock Options Exercised
Compensation cost
Sharebased Compensation Arrangement By Sharebased Payment Award Compensation Cost1
Unrecognized compensation expense related to options
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
Number of Shares
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Roll Forward
Outstanding at January 1, 2022
Granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
Vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period
Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
Outstanding at December 31, 2022
Weighted Average Grant Date Fair Value per Share
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value Roll Forward
Outstanding at January 1, 2022
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
Granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
Vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value
Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
Outstanding at December 31, 2022
Share based compensation arrangement by share based payment award equity instruments other than options in period grant date fair value outstanding.
Total fair value of restricted stock units vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Total Fair Value
Total grant date fair value of restricted stock units outstanding
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options In Period Grant Date Fair Value Outstanding
Unrecognized compensation expense related to non-option
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Share Based Awards Other Than Options
Unrecognized compensation expense, weighted average period for recognition
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Discount on purchase price percentage of fair market value.
Discount on purchase price percentage of fair market value
Discount On Purchase Price Percentage Of Fair Market Value
Common stock available for issuance
Common Stock Capital Shares Reserved For Future Issuance
Milestone rights liability.
Commitments and Contingencies [Line Items]
Commitments and Contingencies [Table]
Commitments And Contingencies [Table]
Commitments And Contingencies [Table]
Master lease agreement with enterprise.
Master Lease Agreement with Enterprise
Master Lease Agreement With Enterprise [Member]
Vehicle Leases
Vehicles [Member]
Office.
Office Lease
Office [Member]
Russell Ranch Road II LLC.
Russell Ranch Road II LLC
Russell Ranch Road I I L L C [Member]
Marlborough lease.
Marlborough Lease
Marlborough Lease [Member]
Equipment
Equipment [Member]
Commitments And Contingencies [Line Items]
Commitments And Contingencies [Line Items]
Milestone rights liability
Milestone Right Liability
Lease repurchase description.
Lease initial term
Lessee Operating Lease Term Of Contract
Lease renewal option
Lessee Operating Lease Renewal Term
Lease renewal options
Lessee Operating Sublease Option To Extend
Lessee,option to extend [true false]
Lessee Operating Sublease Existence Of Option To Extend
Operating lease costs
Operating Lease Cost
Lease, description
Sale Leaseback Transaction Lease Terms
Security deposit
Security Deposit
Lease repurchase, amount
Sale Leaseback Transaction Net Book Value
Lease repurchase description
Lease Repurchase Description
Financing liability
Finance Lease Liability
Weighted average remaining lease term (in years)
Finance Lease Weighted Average Remaining Lease Term1
Weighted average discount rate
Finance Lease Weighted Average Discount Rate Percent
Interest expense on financing liability
Finance lease liability discounted payments due.
Operating Lease Liabilities Payments Due [Abstract]
2023
Finance Lease Liability Discounted Payments Due Next Twelve Months
2024
Finance Lease Liability Discounted Payments Due Year Two
2025
Finance Lease Liability Discounted Payments Due Year Three
2026
Finance Lease Liability Discounted Payments Due Year Four
2027
Finance Lease Liability Discounted Payments Due Year Five
Thereafter
Finance Lease Liability Discounted Payments Due After Year Five
Total
Finance Lease Liability Discounted Payments Due
Interest payments
Finance Lease Liability Discounted Excess Amount
Debt issuance costs
Finance Lease Liability Discounted Debt Issuance Costs
Total financing liability
Finance Lease Liability Discounted
Payment of long term purchase commitment amendment fee.
Payment of long term purchase commitment, amendment fees
Payment Of Long Term Purchase Commitment Amendment Fee
Purchase Obligation Fiscal Year Maturity [Abstract]
2023
Purchase Obligation Due In Next Twelve Months
2024
Purchase Obligation Due In Second Year
2025
Purchase Obligation Due In Third Year
2026
Purchase Obligation Due In Fourth Year
2027
Purchase Obligation Due In Fifth Year
Long Term Purchase Commitment, Expiration Date
Long-term purchase commitment, renewal time period.
Supply Agreement expiration period
Long Term Purchase Commitment Expiration Date
Supply Agreement renewal period
Longterm Purchase Commitment Renewal Time Period
Number of vehicle leases retired.
Number of vehicle leases replaced.
Number of vehicle leases.
Number of vehicle leases retired
Number Of Vehicle Leases Retired
Number of vehicle leases replaced
Number Of Vehicle Leases Replaced
Number of vehicle leases
Number Of Vehicle Leases
Operating lease rent expenses
Operating Lease Expense
Gain or loss recorded for leases removed
Gain Loss On Termination Of Lease
Operating lease, right-of-use asset
Operating Lease Right Of Use Asset
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Operating Lease Right Of Use Asset Statement Of Financial Position Extensible List
Operating lease, liability
Operating Lease Liability
Operating leases annual increase in rent expense.
Lease expiration month and year.
Percentage of annual increase in lease payment
Operating Leases Annual Increase In Rent Expense
Lease expiration
Lease Expiration Month And Year
Description of right to extension of lease term
Lessee Operating Lease Option To Extend
Lease Cost
Lease Cost
Operating lease liability-current (2)
Operating Lease Liability Current
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Operating Lease Liability Current Statement Of Financial Position Extensible List
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Operating Lease Liability Noncurrent Statement Of Financial Position Extensible List
Total
Weighted average remaining lease term (in years)
Operating Lease Weighted Average Remaining Lease Term1
Variable lease costs
Variable Lease Cost
Cash paid
Operating Lease Payments
Office and vehicle.
office and vehicle
Office And Vehicle [Member]
Year 1
Lessee Operating Lease Liability Payments Due Next Twelve Months
Year 2
Lessee Operating Lease Liability Payments Due Year Two
Year 3
Lessee Operating Lease Liability Payments Due Year Three
Year 4
Lessee Operating Lease Liability Payments Due Year Four
Year 5
Lessee Operating Lease Liability Payments Due Year Five
Thereafter
Lessee Operating Lease Liability Payments Due After Year Five
Total
Lessee Operating Lease Liability Payments Due
Interest expense
Lessee Operating Lease Liability Undiscounted Excess Amount
Defined Benefit Plans And Other Postretirement Benefit Plans Disclosures [Table]
Defined Benefit Plans And Other Postretirement Benefit Plans Disclosures [Table]
Scenario
Statement Scenario [Axis]
Scenario
Scenario Unspecified [Domain]
One year service.
One Year Service
One Year Service [Member]
Two year service.
Two Year Service
Two Year Service [Member]
Defined Benefit Plans And Other Postretirement Benefit Plans Table Text Block [Line Items]
Defined Benefit Plans And Other Postretirement Benefit Plans Table Text Block [Line Items]
Employer matching contribution deferral rate
Defined Contribution Plan Employer Matching Contribution Percent Of Match
Employer matching contribution, percent of employees' compensation
Defined Contribution Plan Employer Matching Contribution Percent
Employers matching contribution vesting percentage
Defined Contribution Plan Employers Matching Contribution Annual Vesting Percentage
Total discretionary matching contributions
Defined Benefit Plan Contributions By Employer
United States
Income Loss From Continuing Operations Before Income Taxes Domestic
Foreign
Income Loss From Continuing Operations Before Income Taxes Foreign
Current
Current Income Tax Expense Benefit Continuing Operations [Abstract]
U.S. federal
Current Federal Tax Expense Benefit
U.S. state
Current State And Local Tax Expense Benefit
Non-U.S.
Current Foreign Tax Expense Benefit
Total current
Current Income Tax Expense Benefit
Deferred
Deferred Income Tax Expense Benefit Continuing Operations [Abstract]
U.S. federal
Deferred Federal Income Tax Expense Benefit
U.S. state
Deferred State And Local Income Tax Expense Benefit
Non-U.S.
Deferred Foreign Income Tax Expense Benefit
Total deferred
Deferred Income Tax Expense Benefit
Valuation allowance
Valuation Allowance Deferred Tax Asset Change In Amount
Total
Deferred Tax Assets Capitalized Research Expenses
Deferred Tax Assets Milestone Rights
Deferred Tax Assets, Tax Deferred Expense (Accrual Adjustment)
Deferred Tax Assets Loss on Purchase Commitment
Deferred Tax Assets Capitalized Costs
Deferred tax assets lease liabilities.
Deferred tax assets interest expense limitation.
Deferred tax assets product revenue and other.
Deferred tax liabilities right of use asset.
Deferred tax assets:
Components Of Deferred Tax Assets [Abstract]
Net operating loss carryforwards
Deferred Tax Assets Operating Loss Carryforwards
Research and development credits
Deferred Tax Assets Tax Credit Carryforwards Research
Capitalized research costs
Deferred Tax Assets Capitalized Research Expenses
Milestone Rights
Deferred Tax Assets Milestone Rights
Accrued expenses
Deferred Tax Assets Tax Deferred Expense Accrual Adjustment
Loss on purchase commitment
Deferred Tax Assets Loss On Purchase Commitment
Non-qualified stock option expense
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
Capitalized patent costs
Deferred Tax Assets Capitalized Costs
Other
Deferred Tax Assets Tax Deferred Expense Other
Lease liability
Deferred Tax Assets Lease Liabilities
Interest expense limitation
Deferred Tax Assets Interest Expense Limitation
Depreciation
Deferred Tax Assets Other
Deferred Product Revenue & Costs
Deferred Tax Assets Product Revenue And Costs
Total net deferred tax assets
Deferred Tax Assets Gross
Valuation allowance
Deferred Tax Assets Valuation Allowance
Net deferred tax assets
Deferred Tax Assets Net
Deferred tax liabilities:
Components Of Deferred Tax Liabilities [Abstract]
Right of use asset
Deferred Tax Liabilities Right Of Use Asset
Other prepaids
Deferred Tax Liabilities Prepaid Expenses
Total deferred tax liabilities
Deferred Income Tax Liabilities
Net deferred tax assets
Deferred Tax Assets Liabilities Net
Effective Income Tax Rate Reconciliation Permanent Items
Effective income tax rate reconciliation expirations of attribute.
Effective income tax rate reconciliation foreign withholding tax.
Federal tax benefit rate
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
Permanent items
Effective Income Tax Rate Reconciliation Permanent Items
Stock based compensation
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
Tax attribute expirations
Effective Income Tax Rate Reconciliation Expirations Of Attribute
Foreign withholding tax
Effective Income Tax Rate Reconciliation Foreign Withholding Tax
Valuation allowance
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
Other
Effective Income Tax Rate Reconciliation Other Adjustments
Effective income tax rate
Effective Income Tax Rate Continuing Operations
Income Taxes [Line Items]
Income Taxes [Table]
Income Taxes [Table]
Income Taxes [Table]
Income Tax Authority
Income Tax Authority [Axis]
Income Tax Authority
Income Tax Authority [Domain]
State
State And Local Jurisdiction [Member]
New Jersey
New Jersey Division Of Taxation [Member]
Connecticut tax authority.
Connecticut
Connecticut Tax Authority [Member]
California division of taxation.
California
California Division Of Taxation [Member]
Income Tax Authority, Name
Income Tax Authority Name [Axis]
Income Tax Authority, Name
Income Tax Authority Name [Domain]
Federal
Internal Revenue Service I R S [Member]
Income Taxes [Line Items]
Income Taxes [Line Items]
Valuation allowance of deferred tax asset
Change in the valuation allowance
Federal operating loss carryforwards
Deferred Tax Assets Operating Loss Carryforwards Domestic
State operating loss carryforwards
Deferred Tax Assets Operating Loss Carryforwards State And Local
Federal operation loss carryforwards, not subject to expiration
Deferred Tax Assets Operating Loss Carryforwards Not Subject To Expiration
Operating Loss Carryforwards Subject To Limitation
Net Operating Loss Carryforward Annual Limitation
Operating loss carryforwards, limitations on use
Operating Loss Carryforwards Limitations On Use
Net operating loss carryforwards
Operating Loss Carryforwards Subject To Limitation
Net operating loss and credit carryforwards, annual use limitation
Net Operating Loss Carryforward Annual Limitation
Deferred tax assets tax credit carryforwards research not expire.
Research and Development Credits, Begin to Expire
Deferred tax assets tax credit carryforwards research expire.
Research and development credits not expire
Deferred Tax Assets Tax Credit Carryforwards Research Not Expire
Research and development credits begin to expire
Research And Development Credits Begin To Expire
Research and development credits expire
Deferred Tax Assets Tax Credit Carryforwards Research Expire
Beginning of Year
Unrecognized Tax Benefits
Gross increases for tax positions of prior years
Unrecognized Tax Benefits Increases Resulting From Prior Period Tax Positions
Gross decreases for tax positions of current year
Unrecognized Tax Benefits Decreases Resulting From Current Period Tax Positions
Settlements
Unrecognized Tax Benefits Increases Resulting From Settlements With Taxing Authorities
Lapse of statute of limitations
Unrecognized Tax Benefits Reductions Resulting From Lapse Of Applicable Statute Of Limitations
End of Year
Unrecognized income tax interest and penalties
Unrecognized Tax Benefits Income Tax Penalties And Interest Expense