April 3, 2019 Michael Castagna Chief Executive Officer MannKind Corporation 30930 Russell Ranch Road, Suite 300 Westlake Village, CA 91362 Re: MannKind Corporation Registration Statement on Form S-3 Filed March 29, 2019 File No. 333-230633 Dear Dr. Castagna: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Tonya K. Aldave at (202) 551-3601 with any questions. Sincerely, Division of Corporation Finance Office of Healthcare & Insurance cc: Carlos Ramirez, Esq.