MannKind Presents Data at 21st Annual Diabetes Technology Meeting
- A Technosphere® Insulin (TI) dose – approximately double the estimated mealtime subcutaneously (SC) injection dose – reduced postprandial glucose excursions (PPGE) without any severe hypoglycemia in the first two hours
- Higher dose of TI resulted in approximately 50 mg/dL improvement in PPGE at 120 minutes
Mealtime control of glucose for patients living with diabetes remains a critical goal. This feasibility study demonstrated that a TI dose – approximately double the estimated mealtime SC injection dose –provided significant reductions in PPGE without severe hypoglycemia. The maximum mean postprandial glucose decreased from 234 to 186 mg/dL and significant reductions in PPGE were observed from 45 to 120 minutes.
“MannKind aspires to be a leader in mealtime control as this is a critical need within the diabetes community,” said
Twenty adult participants (≥ 18 years) with T1D or T2D who were on a stable regimen of basal-bolus insulin therapy were enrolled in this feasibility study. Each subject received an initial dose of TI based on the conversion chart in the current
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